In selective autophagy, receptors are central for cargo selection and delivery.However, it remains yet unclear wheth......

青光眼是全球主要致盲眼病之一，青光眼的视网膜神经节细胞受损为其特征性改变，而这种改变一直被认为是由升高的眼内压影响所致。但随......

视神经蛋白(OPTN)目前被认为是原发性开角型青光眼(POAG),肌萎缩侧索硬化症(ALS)等神经退行性疾病的病理学标记蛋白.OPTN参与不同......

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<正> Aim: A recent study found that the Optineurin (OPTN) gene was mutated in families with primary open angle glaucoma ......

Amyotrophic lateral sclerosis(ALS)is a devastating neurodegenerative disorder characterized by loss of upper and lower m......

目的:研究Optineurin(OPTN)及其两种疾病相关突变体在细胞内蛋白质量控制的不同,从细胞分子生物学水平揭示其引起不同疾病的可能机......

Glaucoma is a common neurodegenerative disease that can cause blindness and occurs worldwide. Currently, lowering intrao......